Hyzaar 50/12.5mg Tablets (Generic Equivalent)

Hyzaar contains a combination of hydrochlorothiazide and losartan. Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention. Losartan is a angiotensin II receptor antagonist. Losartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow. Hyzaar is used to treat high blood pressure (hypertension). It is also used to lower the risk of stroke in certain people with heart disease. Hyzaar may also be used for purposes other than those listed in this medication guide.

The health and medical information provided here is for general purposes only and is not a substitute for the expertise and judgment of your physician, or other health care professional. It should not be understood to indicate that the use of this medicine is safe, appropriate or effective for you. Always consult your health care professional before using this, or any other, drug.

Do not use Hyzaar if you are allergic to hydrochlorothiazide or losartan, or if you are unable to urinate. Do not use Hyzaar without telling your doctor if you are pregnant. Losartan may cause injury and even death to the unborn baby if you take it during the second and third trimesters of pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment.

Before using Hyzaar, tell your doctor if you have congestive heart failure, kidney or liver disease, asthma, low or high blood levels of potassium, gout, lupus, diabetes, or an allergy to sulfa drugs.

Hyzaar can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can lower your blood pressure and may increase some of the side effects of Hyzaar.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor`s instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.

Do not use potassium supplements or salt substitutes while you are taking Hyzaar, unless your doctor has told you to. In rare cases, Hyzaar can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have muscle pain, tenderness, or weakness especially if you also have fever, nausea or vomiting, and dark colored urine.

Get emergency medical help if you have any of these signs of an allergic reaction to Hyzaar: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. In rare cases, Hyzaar can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have muscle pain, tenderness, or weakness especially if you also have fever, nausea or vomiting, and dark colored urine. Stop using Hyzaar and call your doctor at once if you have a serious side effect such as:

feeling light-headed, fainting;

swelling, rapid weight gain;

fast or pounding heartbeats;

pale skin, easy bruising or bleeding;

urinating less than usual, or not at all;

jaundice (yellowing of the skin or eyes); or

dry mouth, increased thirst, drowsiness, restless feeling, confusion, increased urination, fast heart rate, fainting, or seizure (convulsions).

Less serious Hyzaar side effects may include:


stomach pain;

back pain;

dizziness, tired feeling;

skin rash;

runny or stuffy nose, sore throat; or

dry cough.

Take Hyzaar exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results from this medication.

Take Hyzaar with a full glass (8 ounces) of water.

Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking Hyzaar, which can lead to severely low blood pressure or a serious electrolyte imbalance.

To be sure this medication is helping your condition, your blood pressure will need to be checked on a regular basis. Your kidney function may also need to be tested. Do not miss any scheduled appointments.

Hydrochlorothiazide can interfere with the results of a thyroid test. Tell any doctor who treats you that you are using Hyzaar.

If you are being treated for high blood pressure, keep using Hyzaar even if you feel fine. High blood pressure often has no symptoms.

Store Hyzaar at room temperature away from moisture and heat.